Projects
Translational MS research UMSC. Hasselt University
From genotype to immunophenotype in multiple sclerosis. KU Leuven
The development of preclinical models to evaluate combinatorial strategies for augmenting the potency of dendritic cell-based immunotherapy Vrije Universiteit Brussel
Two novel strategies are under development for the treatment of malignant melanoma: immunotherapy and molecular-targeted ...
Immunological memory of the macrophage niche (MacNicheMemo). Vrije Universiteit Brussel
Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs) Ghent University
Communication between cells is of essential importance in all physiological and pathological processes in multicellular organisms. A relatively recently discovered method of cell-cell communication consists of the formation of long cell projections by one cell that may reach to and dock onto other, distantly located, cells, resulting in exchange of biological information between these previously unconnected cells. These cell projections have ...
Recent data predict an increased risk for virus transmission upon Japanese encephalitis virus (JEV) introduction in pigs: Study of JEV induced immune responses and evaluation of diagnostic tests Ghent University
The one year JEV-PIG project that was granted during the RF call of 2017 allowed our consortium to perform an in vivo infection study with Japanese encephalitis virus (JEV) in pigs to compare JEV pathogenesis and humoral immune responses after infection via 3 inoculation (oronasal inoculation to mimic the vector-free transmission and intradermal inoculation of virus alone or of virus combined with mosquito saliva to mimic vector-mediated ...
To enhance the research capacity and evidence based medical practice in tropical and poverty related diseases in Ethiopia Institute of Tropical Medicine
Building on the needs jointly identified during FA3-III, in the present proposal, we ...
Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID) Ghent University
Common variable immunodeficiency disorder (CVID) is a group of diseases in which the capacity to produce antibodies (immunoglobulins, Igs) against microbial infections is impaired. There is a marked decrease in one or more Ig classes and the number and/or function of certain B lymphocyte subsets may be reduced. In addition to an increased susceptibility to infections, CVID is also associated with auto-immune and malignant conditions. The ...
Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria. Institute of Tropical Medicine
Overall Goal: To identify artemisinin-based combination treatments (ACT) that can be safely and efficaciously used to treat women with malaria in their second and third trimester of pregnancy. This will be attained through the following strategies: 1. Research: To determine the safety and efficacy of 4 ACTs when administered to pregnant women during the second and the third trimester with P. falciparum infection and collect explanatory ...