Persistence in Streptococcus pneumoniae infections: elucidation of the importance of persister cells in chronic and recurrent infections University of Antwerp
Katholieke Universiteit Leuven, Catholic University of Louvain, Laboratory for Microbiology, Parasitology and Hygiene (LMPH)
Streptococcus pneumoniae is an important human pathogen, as it is one of the most common causes of community-acquired pneumonia and otitis media. Several issues arise when battling these infections. First, replacement of vaccine-serotypes by new ones has been observed. Second, antibiotic resistance is an emerging problem. Also, antibiotic persistence is considered an important, yet underexposed phenomenon. Persister cells are a subpopulation of ...