Publications
In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system Vrije Universiteit Brussel
OBJECTIVES: To evaluate the in-vitro and in-vivo effects on monoaminergic neurotransmission of ASS234, a promising multitarget-directed ligand (MTDL), for Alzheimer's disease (AD) therapy.
METHODS: In vitro was explored the effect of ASS234 on the monoaminergic metabolism in SH-SY5Y and PC12 cell lines, and remaining activity of both monoamine oxidase (MAO) isoforms was assessed. The corresponding dopamine (DA), homovanillic acid ...
Uncoupling of in-vitro identity of embryonic limb derived skeletal progenitors and their in-vivo bone forming potential KU Leuven
In-Vivo, In-Vitro and In-Silico methods for Small Molecule transfer across the BBB KU Leuven
In-vitro and in-vivo evaluation of enteric-coated starch-based pellets prepared via extrusion/spheronisation Ghent University
In-vitro and in-vivo evidence for the anti-inflammatory activity of hop bitter acids in mouse Ghent University
In-vitro maturation of oocytes versus conventional IVF in women with infertility and a high antral follicle count Vrije Universiteit Brussel
STUDY QUESTION: Is one cycle of IVM non-inferior to one cycle of conventional in IVF with respect to live birth rates in women with high antral follicle counts (AFCs)?
SUMMARY ANSWER: We could not demonstrate non-inferiority of IVM compared with IVF.
WHAT IS KNOWN ALREADY: IVF with ovarian hyperstimulation has limitations in some subgroups of women at high risk of ovarian stimulation, such as those with polycystic ovary ...
Inertial control: a novel technique for in-vitro analysis of foot function KU Leuven
Recovery and in-vitro culture of early preantral guinea pig follicles Vrije Universiteit Brussel
This manuscript describes the isolation of intact preantral guinea pig follicles and their subsequent stepwise culture development. Intact early ...