Projects
In vivo imaging of synaptic density and white matter integrity as noninvasive biomarkers for spinal cord injury and repair. University of Antwerp
Non-invasive quantitative imaging of oxygen concentration distributions in vivo by use of magnetic resonance imaging (MRI) Ghent University
The developed magnetic resonance imaging (MRI) method should enable us to image the oxygen concentration in tumors. This technique could be of great significance in the biologicat optimatization of cancer treatment by use of ionaizing irradiation.
Imagine Trypanosomes: a novel model for in vivo monitoring of Trypanosoma brucei infections by means of bioluminescence and magnetic resonance imaging. University of Antwerp
Establishing a multimodal preclinical imaging platform for the in vivo assessment of spinal cord injury outcome and therapeutic response. University of Antwerp
Biomarker and therapy development through in vivo Molecular Imaging of small animals. University of Antwerp
Topographical organization of object selective areas in the visual cortex of the macaque monkey. KU Leuven
Functional characterization of human neurons in the human-mouse chimeric model for Alzheimer’s disease KU Leuven
Alzheimer’s disease (AD) is the most common neurodegenerative disorder and main cause of dementia among the elderly. It is estimated that about 50 million are affected with dementia worldwide and the prevalence is expected to triple by 2050(1.2). For most of the AD cases (late-onset), 40 susceptibility loci may contribute to the AD according to the genome-wide association studies(3). While for early-onset AD, mutations in genes encoding ...
Fluorine-19 Magnetic Resonance Imaging as a Potential Tool in Preclinical Research --- With Focus on Diabetes KU Leuven
Diabetes remains one of the increasing threats to human health with over 422 million people suffering from the disease all over the world. Despite the advancements in understanding the disease and improvements in treatment, diagnosis and early prevention with effective monitoring of pre- and post- therapy of the disease is still urgently needed. Hereby, the function and mass of pancreatic islets (PIs) and in particular their beta cells play ...
Multimodal dual-imaging-derived biomarkers for unravelling host response from lung disease progression in cystic lung fibrosis, infection and therapy KU Leuven
Despite the significant advances made by the introduction of imaging techniques for lung diseases and fungal infection research, there are still important gaps where we identify three priorities we want to address with our project. First, we will address the need for alternative antifungal treatment approaches by investigating fungicidal combinatorial treatment in vivo in mouse models of invasive pulmonary aspergillosis (IPA) (context of ...