Studying deficits in the neurovascular coupling in a mouse model of Alzheimer's disease: an in vivo MRI approach. University of Antwerp
The neurovascular coupling, essential for normal brain function, is compromised already in an early stage of Alzheimer's Disease. In the present project we want to study the hemodynamic coupling to neuronal activity changes using functional magnetic resonance imaging. We believe that accurate early identification of these pathological processes would be a significant benefit for the development of new treatment strategies.