Viral Oncology: molecular biology and pathogenesis of post-transplant lymphoproliferative disorder (PTLD) KU Leuven
Post-transplantation lymphoproliferative disorder (PTLD) is a rare but life-threatening disorder following solid organ (SOT) and hematopoietic stem cell transplantation (HSCT). The disorder is caused by drug-induced reduced immune surveillance leading to an uncontrolled proliferation of lymphocytes. Although rare, incidence has clearly increased during the last two decades with estimated incidence rates of 1-20% in SOT recipients. After it is ...