Projects

Henipaviruses are negative-strand RNA viruses in the Paramyxoviridae family with currently five species: Cedar, Ghanaian bat, Hendra, Mojang and Nipah henipaviruses. They are naturally harbored by pteropid fruit bats (flying foxes) and microbats of several species found throughout the tropics and subtropics. Henipavirus outbreaks in humans have occurred in northern Australia and Southeast Asia since the mid-1990s. Hendra virus (HeV) has been ...

The purpose of this project is to identify henipavirus inhibitors and a small animal model of henipavirus replication in BSL-2 containment.

Over the last years, several viruses pathogenic to human viruses are believed to have originated in bats, including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS)-related coronaviruses, as well as filoviruses, such as Ebola- and Marburgvirus, or Henipaviruses, such as Nipah and Hendra virus. In Cameroon, bats are hunted and eaten in some parts of the country, particularly the Southwest Region and these close ...