Projects
Functional genomics in human blood platelets. KU Leuven
Talking about Human Kinds: The Normative Implications of Generic Stereotypes KU Leuven
Stereotypes are the pictures that come to mind when thinking about a category of people. While most of these generalizations are quite innocent, some of them are so bad that it seems wrong just to believe in them. According to the traditional view, stereotypes are epistemically and morally problematic because they are negative and false universalizations that only prejudiced people would hold. This traditional view is still very influential, ...
Modeling human motion from a neuromechanical perspective: from a generic mechanical model towards a subject-specific cybernetic system. KU Leuven
A genetic approach for the study of Notch signaling in normal and malignant hematopoiesis in humans Ghent University
Human Kinetics (Biomechanics) KU Leuven
Hip fracture (HF) is one of the most serious consequences of falls in the elderly. Many of HF patients do not regain pre-fracture functional status and lose their ability to walk2,3. Walking ability is an important factor to estimate the post-operatory functional ability prognosis4. Studies assessing walking ability in HF patients have used simple performance tests5,6 or have not looked beyond spatio-temporal parameters. However, kinematic ...
Research towards the molecular pathogenesis of chlamydophila psittaci in human macrophages and epithelial cells: genomics, proteomics and methylomics of highly and less virulent strains. Ghent University
The project aims at getting more insight into the bacterium host cell interactions, focusing on the molecular pathogenesis en reprogrammation of the host cell by this obligate intracellular bacterium. For that purpose we can make use of well identified chlamydophila psittaci strains with well documented differences in virulence demonstrated both in vitro and in vivo.
Genetics in everyday life. A qualitative study of individuals at risk of hereditary breast and ovarian cancer (BRCA) and Huntington’s disease (HD) about fears of genetic discrimination KU Leuven
For decades, as our understanding of human genetics has continued to advance, socio-ethical and legal scholars have raised questions and concerns about the ethical and social implications (ELSI issues) of genetics. One specific ELSI concern is that increased knowledge and applications of human genetics might lead to new forms of negative treatment, discrimination, and stigmatisation. In the nineties, several Western countries responded to ...
MOLECULAR DIAGNOSTICS IN AUTISM SPECTRUM DISORDER: NEXT GENERATION SEQUENCING AND FACIAL PHENOTYPING IN MEDICAL GENETICS KU Leuven
Despite considerable progress in the genetics of autism spectrum disorder (ASD) in the past decade, molecular diagnostics for patients with ASD remains a great challenge due to the complex genetic architecture of ASD. In clinical genetics, an etiological distinction is usually made between ASD patients with Mendelian causes (i.e. driven by a highly penetrant rare variant) and patients with multifactorial causes (i.e. driven by many genetic ...