Projects
Developing a combined screening and molecular triage approach for cervical cancer based on HPV detection, quantification, genotyping and DNA methylation in self-samples. University of Antwerp
Coalition to strengthen the HPV Immunization Community (CHIC). University of Antwerp
Sustaining, deepening and expanding the Sub-Saharian HPV research network (WAKA-HPV Africa). University of Antwerp
P16 in HPV related Head and Neck Carcinoma: Taken for surrogate marker, but being the radiobiological master switch? KU Leuven
Human papilloma virus (HPV) related head and neck cancer (HNSCC) is becoming a worldwide epidemic. The clinical behavior of these HNSCC’s differs very much from that of classical smoking and alcohol related HNSCC but the molecular basis for this is not understood: First, these tumors respond far better to radiotherapy than classical HNSCC. Further in contrast to classical HNSCC these tumors are unresponsive to hypoxia targeted therapy ...
HPV infection in oropharyngeal carcinoma: incidence and prognostic impact Ghent University
The human papillomavirus (HPV) is the strongest risk factor for oropharyngeal cancer. HPV-associated head-and-neck cancers have a survival advantage and appear to respond better to treatment. To date, no data are available about the incidence of HPV-related oropharyngeal cancer in Flanders. The aim of this study is to determine the incidence and correlate it with treatment outcome and underlying mechanisms.
Vaccinating Europe to protect against the cancers caused by HPV (PROTECT-EUROPE). University of Antwerp
Evaluating the predictive value of a primary high-risk HPV DNA and reflex methylation marker test strategy in first-void urine to identify women with clinically relevant cervical disease in need of referral. University of Antwerp
Early detection of cervical cancer in hard-to-reach populations of women through portable and point-of-care HPV testing Ghent University
Cervical cancer is the 4th most common cancer in women worlThe ELEVATE project sets a multidisciplinary team comprising manufactures and experts from Europe and the Community of Latin American and Caribbean States, to improve the global adequacy and coverage of cervical cancer screening, particularly to specific populations of women that by not being regularly screened (hard-to-reach populations) are at higher-risk to develop cervical ...
A Community-based HPV screening implementation in Low-Income countries Ghent University
Global implementation of cancer screening can be hindered by differences in cultures and available resources between countries. The EU-funded CHILI project will address this challenge by determining the acceptability, feasibility and cost-effectiveness of the ELEVATE cervical cancer screening tool for women in low-income countries. This portable, battery-powered device comprises a human papillomavirus DNA test and a proteomic biomarkers ...