Low prevalence of vitamin D deficiency in Ugandan HIV-infected patients with and without tuberculosis University of Antwerp Institute of Tropical Medicine
Adaptation of Mycobacterium tuberculosis to impaired host immunity in HIV-infected patients Institute of Tropical Medicine
Background. It is unknown whether immunosuppression influences the physiologic state of Mycobacterium tuberculosis in vivo. We evaluated the impact of host immunity by comparing M. tuberculosis and human gene transcription in sputum between human immunodeficiency virus (HIV)-infected and uninfected patients with tuberculosis.
Methods. We collected sputum specimens before treatment from Gambians and Ugandans with pulmonary tuberculosis, ...
Maraviroc modifies gut microbiota composition in a mouse model of obesity: a plausible therapeutic option to prevent metabolic disorders in HIV-infected patients. KU Leuven
iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy Institute of Tropical Medicine Vrije Universiteit Brussel
BACKGROUND: HIV therapeutic vaccination aims to improve the immune responses against HIV in order to control viral replication without the need for combined antiretroviral therapy (cART). iHIVARNA-01 is a novel vaccine combining mRNA delivery and T-cell immunogen (HTI) based on conserved targets of effective antiviral T-cell responses. In addition, it holds adequate stimuli required for activating antigen presenting cells (APC)s and ...