The role of glucagon and endocrine FGFs in orchestrating the complex endocrine and metabolic responses to critical illness KU Leuven
Critically ill patients who need vital organ support to avoid imminent death develop remarkable endocrine and metabolic changes that have been related with morbidity and risk of death. Neuroendocrine changes affect growth hormone, thyroid hormone and cortisol, among others. Metabolic changes include mitochondrial dysfunction, low cholesterol, high triglyceride and bile acid levels, and disturbed glucose homeostasis manifested by insulin ...