Projects
Development of an innovative multiscale computational model to quantitatively unravel the role of cell-matrix mechanics in angiogenesis KU Leuven
The ability of cells to migrate through a tissue in the human body is vital for many processes such as tissue development, growth and regeneration. At the same time, abnormal cell migration is observed in many diseases such as cancer. In order to discover the origin of these abnormalities and develop new treatment strategies, an improved understanding of the cell migration process and its regulation is required. Mechanics of the cell and the ...
The role of mechanics in cell culture for micro-tissue fabrication. A model-based study using self-propelled particles KU Leuven
In tissue engineering, stem cells are used to produce artificial constructs that can improve or replace biological tissue. The production of these constructs often involves a cell culture step, in which cells are multiplied and assembled in ‘micro-tissues’ with desired tissue properties. To ensure product quality, the physical micro-environment of single cells must be well-controlled during this step. Yet, the formation of this ...