Projects
Next generation phenotyping and genotyping in inherited primary cardiac arrhythmia syndromes and cardiomyopathies KU Leuven
The relation between the genotype and phenotype of primary arrhythmia syndromes (PAS) and cardiomyopathies (CMP) is complex and ever expanding. In the first part of this thesis project, we evaluated the value of both novel and existing electrocardiographic parameters in the diagnosis and prognosis of these patients. We proposed a novel method for evaluation of the QT interval based on the patient’s own QT rate dependence profile obtained from ...
Herpesvirus genotyping and phenotyping to the adjustment of anitviral chemotherapy in immunocompromised cancer patients. KU Leuven
Developing a combined screening and molecular triage approach for cervical cancer based on HPV detection, quantification, genotyping and DNA methylation in self-samples. University of Antwerp
Elucidating the link between HLA-presentome and different clinical presentations of cutaneous leishmaniasis with Nanopore HLA genotyping. University of Antwerp
Toxosafe: Risk of Infection of consumption meat with Toxoplasma gondii: optimization of detection, prevalence determination, genotyping and research into the immunological background of parasite clearance from tissues Ghent University
In order to verify the correlation between the seropositivity and the infectivity of the meat, will be positive-known companies can be selected and monitored: there will be piglet from weaning to slaughter are serologically tested monthly. At slaughter will be taken in tissue samples from the animals sero which will then be tested by means of qPCR for the presence of tissue cysts. From the PCR positive salen the infecting T. gondiistarn will ...
Modelling the risk of P. vivax infections through microsatellites genotyping and Circumsporozoite protein (CSP) ELISA Institute of Tropical Medicine
Resistance genotyping for the optimization of anti-HCV treatment. KU Leuven
Chronic hepatitis caused by the hepatitis C virus (HCV) is a serious global health problem. More than 170 million people around the world are currently HCV infected. A minority of patients spontaneously clears the virus, and the remaining with chronic infection are at risk for disease progression potentially leading to liver cancer and death. Although viral clearance can be achieved in a large number of chronically infected patients through ...