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Epidemiologie, predictie en preventie van type 1 diabetes: geen fictie in België.[Epidemiology, prediction and prevention of type 1 diabetes: no fiction in Belgium]. Vrije Universiteit Brussel
The achievements of the Belgian Diabetes Registry (BDR) over a period of almost 20 years are described. This registry is a national and multicentric initiative that collects blood samples and information from diabetes patients and their relatives and treats the results in a confidential and protected way. Not only could the size of the health care problem 'diabetes' finally be quantified and monitored in Belgium for the age group 0-39 years, but ...
Therapies aimed at preservation or restoration of beta cell function in type 1 diabetes Vrije Universiteit Brussel
Type 1 diabetes is caused by an immune mediated destruction of the insulin-secreting beta cells in the pancreas. The disease can become clinically apparent at any age. At clinical diagnosis, there is invariably some residual beta cell function. Recent studies--including one mainly conducted in Belgium--have provided proof of principle that short-term humanized anti-T-cell antibody treatment is able to preserve residual beta cell function for at ...
Een patiënt met acute abdominale pijn en krachtverlies Ghent University
Een 44-jarige patiënt wordt opgenomen met acute abdominale pijn en krachtverlies aan het rechterbeen en de rechterarm. Laboratoriumonderzoek wijst op een acutefasereactie, gestoorde levertests en een progressieve nierinsufficiëntie. De patiënt ontwikkelt vervolgens acute testiculaire pijn en een bilateraal gehoor- verlies. Het klinisch beeld komt overeen met een polyarteriitis nodosa (PAN) en dit wordt histopathologisch bevestigd. Een hepatitis ...
Een Vlaming met reisgerelateerde acute hepatitis E KU Leuven
Hepatitis E virus (HEV) is a frequent cause of acute hepatitis in central an southeast Asia, the Middle East, parts of Africa an Mexico. Its incidence in the US and Europe appears to be very low with most of the sporadic cases linked to a history of traveling to endemic areas. The major mode of transmission is faeco-oral via faecally contaminated drinking water. Acute HEV infection can present as an anicteric or icteric hepatitis. Fulminant ...
Een groot myxoom in het rechter atrium KU Leuven
Pseudoxanthoma elasticum: een metabole bindweefselaandoening Ghent University
Nieuwe behandelingsmogelijkheden voro diabetes mellitus type 2 KU Leuven
In treating diabetes type 2 we endeavor to improve the quality and quantity of life by reducing both micro- and macrovascular side-effects. With the current treatments our therapeutic goals are however obtained only scantily. This often leads to a delayed treatment with insulin injections. Both patient and physician contribute to this retarded onset of insulin therapy. In this article we review the outcome trials of the new treatment options in ...
Metformine: tijd voor herwaardering van een oud geneesmiddel KU Leuven
Metformin is currently recommended as the first choice for the treatment of type 2 diabetes, particularly in obese patients. Its effectiveness in lowering blood glucose as a consequence of restraining as well hepatic glucose production as insulin resistance is firmly established. Novel insights in the action mechanism of AMP kinase could explain its pleiotropic effects. Current contraindications (especially renal impairment, congestive heart ...