Publications
Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology Vrije Universiteit Brussel
In silico evidence for the horizontal transfer of gsiB, a σ(B)-regulated gene in gram-positive bacteria, to lactic acid bacteria Vrije Universiteit Brussel
gsiB, coding for glucose starvation-inducible protein B, is a characteristic member of the σ(Β) stress regulon of Bacillus subtilis and several other Gram-positive bacteria. Here we provide in silico evidence for the horizontal transfer of gsiB in lactic acid bacteria that are devoid of the σ(Β) factor.
Engineering transcriptional regulation in Escherichia coli using an archaeal TetR-family transcription factor KU Leuven Ghent University Vrije Universiteit Brussel
Regulation of IAA Biosynthesis in Azospirillum brasilense Under Environmental Stress Conditions KU Leuven
Single-cell expression and structure-function analysis of a conserved bacterial GTPase in protection against lethal stress KU Leuven
Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters KU Leuven Flanders Institute for Biotechnology
Cassette recruitment in the chromosomal Integron of Vibrio cholerae Vrije Universiteit Brussel
Integrons confer a rapid adaptation capability to bacteria. Integron integrases are able to capture and shuffle novel functions embedded in cassettes. Here, we investigated cassette recruitment in the Vibrio cholerae chromosomal integron during horizontal transfer. We demonstrated that the endogenous integrase expression is sufficiently triggered, after SOS response induction mediated by the entry of cassettes during conjugation and natural ...
Attenuation of the sensing capabilities of PhoQ in transition to obligate insect-bacterial association Institute of Tropical Medicine
Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes Institute of Tropical Medicine University of Antwerp KU Leuven
Background: Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood-specific diet by both sexes, and obligate bacterial symbiosis. This work describes the comparative analysis of six Glossina genomes representing three ...