Development of new synthetic methods for the preparation of amidines and guanidines. University of Antwerp
In the framework of this project, we want to develop new synthetic methods for (hetero)arenecarboximidamides and guanidines. More specifically transition metal catalyzed strategies involving the use of isonitriles, (hetero)arenes/chloro(hetero)arylzincs and amines/chloroamines for the (hetero)arenecarboximidamide construction, and isonitriles and amines/chloroamines for the guanidine build up will be explored.