Projects
Gene therapy for cystic fibrosis in a mouse model using adeno-associated viral vectors KU Leuven
Cystic fibrosis (CF) is the most common monogenic life-threatening disease in the Caucasian population, caused by mutations in CFTR, a chloride/bicarbonate channel that regulates fluid transport across epithelium of different organs (airways, pancreas, intestine, sweat glands and vas deferens). CF affects multiple organs, but lung pathology is the major clinical manifestation. Mutations in the CFTR gene lead to an imbalance ...
The GEne Therapy INnovation Training Network KU Leuven
Drug discovery and gene therapy KU Leuven
This valorization program covers an integrated strategy for disease model development, drug discovery and gene therapy approaches. The program is actively exploiting viral vector technology for the development and validation of screening platforms and model systems for drug discovery and gene therapy. The resulting platforms are subsequently advanced in dedicated valorization trajectories. The viral vector technology and services, developed ...