Projects
Crosstalk between MUC13 signalling and the mucosal microbiota in gastric cancer development. University of Antwerp
Role of MUC13 signaling on epithelial barrier disruption in gastrointestinal disorders. University of Antwerp
Gut−Brain Interactions in Visceral Pain and the Regulation of Food Intake KU Leuven
Neurohumoral gut−brain signals are part of an integrated interoceptive system which is continuously signaling homeostatic information to the brain; normally this remains largely unperceived. Dysfunctional gut−brain signaling has been implicated in both functional (i.e. unexplained) gastrointestinal (GI) disorders, characterized by visceral pain, and food intake disorders, such as obesity. Both groups of conditions are highly prevalent and ...
The role of central neurotransmittersystems and psychological factors in the perception and suppression of visceral pain in health. KU Leuven
Research in the domain inflammation. University of Antwerp
Micro-aspiration versus altered neural control in the pathogenesis and treatment of extra-esophageal manifestations of gastro-esophageal reflux disease. KU Leuven
Impact of the bacterial colonic fermentation on future colorectal cancer risk after bariatric surgery. KU Leuven
Neuro-hormonal control of hunger, nutrient tolerance and food intake : from nutrient sensing to reward sensitivity. KU Leuven
Intense signalling occurs between the gastrointestinal tract and the brain. Under normal conditions, most of these signals are not perceived. We will test the hypothesis that this “Gut-to-Brain” signalling is in fact crucial for the control of food intake. We propose that the capacity for the stomach to relax during food intake, as well as the activation of anti-nociceptive pathways during meal ingestion are crucial determinants of the volume ...