Single-cell sorting and DNA profiling for complex forensic casework KU Leuven
Crime scene and rape kit samples often contain cells from multiple donors leading to complex DNA mixtures. Various methods have been developed in all stages of the process including differential extraction to separate epithelial from sperm cells and the deconvolution of the mixtures using probabilistic genotyping. Despite all efforts, partial profiles and complex mixtures still all too often compromise the resolution of cases leaving victims ...