Publications
The fetal patient - ethical aspects of fetal therapy KU Leuven
Fetal Diagnosis and Therapy during the COVID-19 Pandemic: Guidance on Behalf of the International Fetal Medicine and Surgery Society KU Leuven
The outcome of monochorionic diamniotic twin gestations in the era of invasive fetal therapy Vrije Universiteit Brussel KU Leuven
OBJECTIVE: The purpose of this study was to document pregnancy and neonatal outcome of monochorionic diamniotic twin pregnancies.
STUDY DESIGN: This observational study describes a prospective series included in the first trimester in 2 centers of the Eurotwin2twin project.
RESULTS: Of the 202 included twin pairs, 172 (85%) resulted in 2 survivors, 15 (7.5%) in 1 survivor, and 15 (7.5%) in no survivors. The mortality was 45 of 404 ...
Prediction of outcome in isolated congenital diaphragmatic hernia and its consequences for fetal therapy Vrije Universiteit Brussel KU Leuven
Congenital diaphragmatic hernia (CDH) can be diagnosed in the prenatal period either as part of other anomalies or as an isolated birth defect. The clinical impact of this surgically correctable anatomical defect lies in its impairment of lung development. Currently, up to 30% of babies with isolated CDH die from the consequences of lung hypoplasia and/or pulmonary hypertension. Antenatal prediction of outcome essentially relies on the ...
Psychosocial aspects of invasive fetal therapy as compared to prenatal diagnosis and risk assessment Vrije Universiteit Brussel KU Leuven
OBJECTIVE: To explore the psychosocial impact of invasive fetal therapy (FT).
METHODS: We studied 100 consecutive patients scheduled for invasive FT. Contemporary controls were women undergoing (1) invasive prenatal diagnosis (AC/CVS) and (2) first trimester risk assessment of aneuploidy (NT), and (3) women who declined the latter (CTR). Prior to the procedure, participants completed the Beck Depression Inventory II, the State-Trait ...
Assessment of fetal cardiac function before and after therapy for twin-to-twin transfusion syndrome Vrije Universiteit Brussel KU Leuven
OBJECTIVE: We sought to assess fetal cardiac function in monochorionic twins before and after therapy for twin-to-twin transfusion syndrome (TTTS) and compare it with control subjects.
STUDY DESIGN: We conducted prospective longitudinal assessment of fetal cardiac function in cases undergoing curative fetal therapy for TTTS (n = 39) until 4 weeks postoperatively and in uncomplicated monochorionic twins (n = 23). Fetal cardiac function ...