Projects
The role of H3K9 methylation by Euchromatic Histone Methyl Transferases (EHMT1/2) in controlling cardiac myocyte growth and proliferative responses during health and disease. KU Leuven
Stem Cell and Stromal Vascular Fraction Treatment for Penile Tunica Albuginea and Urethral Fibrosis KU Leuven
Fibrosis is a wound healing disorder and it is defined by the excessive accumulation of fibrous connective tissue, such as collagen and fibronectin, in and around inflamed or damaged tissue. Although collagen and fibronectin deposition is an indispensable and, typically, reversible part of wound healing, normal tissue repair can evolve into a progressively irreversible fibrotic response if the tissue injury is severe or repetitive or if the ...
The human progenitor cell niche: research on differentiation mechanisms. KU Leuven
Development and exploitation of test systems to evaluate therapies for peroxisomal leukodystrophies. KU Leuven
Launch of a microbiome service platform. University of Antwerp
Exploration of the pharmacokinetics of clindamycin and its metabolites in special patients: from bioanalysis to clinical relevance KU Leuven
When antibiotics are administered to special patients like pregnant women as prophylactic drugs during fetal surgery, as well as during orthopedic and trauma surgery infections, the metabolism and pharmacokinetics are often different from reference patients without these specific characteristics. Furthermore, drug-drug interactions (DDIs) can also be relevant in the event of co-administration of drugs. The research of this dissertation will ...
A multidisciplinary study for the exploitation of biodegradable nanocarriers for targetted drug delivery to preterm newborn lungs KU Leuven
SymBioSys: Computationally disentangling cellular heterogeneity KU Leuven
Building relevant Zika virus infection models to study neuroinvasiveness and vertical/sexual transmission and to assess the potential of novel antiviral strategies KU Leuven
Arboviruses are viruses that are transmitted among vertebrate hosts by arthropods, typically ticks and mosquitoes. Among this group of viruses are important human pathogens that can cause severe and long-term complications. These pathogens include chikungunya virus (CHIKV) and Zika virus (ZIKV), whose re-emergence has been recognized as a global health challenge. Acute CHIKV infections are characterized by fever, myalgia and polyarthritis, ...