Exploration of the pharmacokinetics of clindamycin and its metabolites in special patients: from bioanalysis to clinical relevance KU Leuven
When antibiotics are administered to special patients like pregnant women as prophylactic drugs during fetal surgery, as well as during orthopedic and trauma surgery infections, the metabolism and pharmacokinetics are often different from reference patients without these specific characteristics. Furthermore, drug-drug interactions (DDIs) can also be relevant in the event of co-administration of drugs. The research of this dissertation will ...