Publications
Ovarian Function and Fertility Preservation in Breast Cancer: Should Gonadotropin-Releasing Hormone Agonist be administered to All Premenopausal Patients Receiving Chemotherapy? KU Leuven
Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe Vrije Universiteit Brussel
Purpose: Oncofertility focuses on providing fertility and endocrine-sparing options to patients who undergo life-preserving but gonadotoxic cancer treatment. The resources needed to meet patient demand often are fragmented along disciplinary lines. We quantify assets and gaps in oncofertility care on a global scale.
Methods: Survey-based questionnaires were provided to 191 members of the Oncofertility Consortium Global Partners ...
First live birth after fertility preservation using vitrification of oocytes in a woman with mosaic Turner syndrome Vrije Universiteit Brussel
PURPOSE: To report the case of a young woman diagnosed with Turner syndrome (TS) who achieved a live birth using her own oocytes that had been vitrified for fertility preservation.
METHODS: A 25-year-old woman with mosaic (45,X/46,XX) TS was referred for fertility preservation (FP) counseling. Serum anti-Müllerian hormone (AMH) level was normal (6.4 µg/L). In view of the unpredictable rate of follicle loss in TS individuals, she ...
Combining fertility preservation procedures to spread the eggs across different baskets Vrije Universiteit Brussel
STUDY QUESTION: What is the reproductive potential following combinations of ovarian stimulation, IVM and ovarian tissue cryopreservation (OTC) in female patients seeking fertility preservation (FP)?
SUMMARY ANSWER: In selected patients, combining different FP procedures is a feasible approach and reproductive outcomes after FP in patients who return to attempt pregnancy are promising.
WHAT IS KNOWN ALREADY: FP is increasingly ...
ESHRE guideline: female fertility preservation KU Leuven
Strategies for fertility preservation in young early breast cancer patients KU Leuven
Fertility preservation in boys Vrije Universiteit Brussel
Spermatogonial stem cells (SSC) are the founder cells of spermatogenesis and are responsible for the lifelong production of spermatozoa. The cryopreservation and transplantation of these cells has been proposed as a fertility preservation strategy for young boys at risk for stem cell loss, i.e. patients undergoing chemotherapy for cancer or as a conditioning treatment for bone marrow transplantation. To prevent lifelong sterility in boys, two ...
Fertility preservation in boys : spermatogonial stem cell transplantation and testicular grafting Vrije Universiteit Brussel
Fertility Preservation in Childhood Cancer Vrije Universiteit Brussel
Survivors of childhood cancer are at risk for long-term treatment-induced health sequelae, including gonadotoxicity and iatrogenic infertility. At present, for prepubertal boys there are no viable clinical options to preserve future reproductive potential. We investigated the effect of a pubertal induction regimen with gonadotrophins on prepubertal human testis xenograft development. Human testis tissue was obtained from patients with cancer ...