Myotonic dystrophy type 1 (DM1)-specific induced pluripotent stem cells (iPS): an innovative platform for myogenic and cardiomyogenic differentiation and validation of novel therapeutic approaches Vrije Universiteit Brussel
Myotonic dystrophy type 1 (DM1) or Steinert's disease is a relatively common genetic disorder that results in a gradual degeneration of the function of the skeletal muscles and the heart. There is currently no cure or effective treatment available. The disease is caused by a genetic defect resulting in a toxic gene product. However, the exact mechanisms of this disease are not fully understood. The objectives of this project is to better ...