BruStem: Regenerative medicine of the liver using synergistic mixtures of immature or mature human hepatocytes with mesenchymal stem/progenitor cells or with hepatic stellate cells. Vrije Universiteit Brussel
Etienne Sokal, Leo A van Grunsven
Université catholique de Louvain, Physiology, Toxicology, Dermato-cosmetology and Pharmacognosy, Cell Biology and Histology
The aim of the project is to explore alternative cell candidates for liver regenerative medicine. Mesenchymal stem/progenitor cells from intra and extrahepatic sources are specifically studied with respect to their proliferation and hepatogenic differentiation potential. In parallel, the selected cells will be investigated regarding their possible use as an in vitro cell model for toxico-pharmacological screening tests. Liver stellate cells will ...