Projects
Flow Cytometry and Cell Sorting Core Facility Uantwerpen (FACSUA) University of Antwerp
Evaluating the effect of sampling site and cryopreservation on blood cell counts for various subpopulations University of Antwerp
Anaesthesia-related allergy: from new insights in pathomechanisms to reliable diagnostic instruments. University of Antwerp
Unraveling defects in the human innate immune response: Diagnosis of inherited disorders in the NF-κB pathway KU Leuven
Primary immunodeficiencies are inherited diseases that predispose children and adults to recurrent bacterial, viral, and/or fungal infections. The awareness for primary immunodeficiencies is still limited in routine clinical practice and many patients are diagnosed too late to prevent life-threatening infections by appropriate therapy. Toll-like/IL-1R (TIR) receptors and the associated NF-κB signaling pathway are important mediators of the ...
Anaesthesia-related allergy: from new insights in pathomechanisms to reliable diagnostic instruments. University of Antwerp
Flow cytometer Ghent University
This application concerns the replacement of a flow cytometer in the Lab. General Biochemistry and Physical Pharmacy. The new (advanced) flow cytometer will be heavily used in research lines which all deal with the design and development of nanomedicines. In the Lab. Toxicology flow cytometry will be used to characterize cells for the development of bio-assays aimed at monitoring the activation of the G Protein-Coupled REceptor.
Particulate matter in calf stables: impact on airway inflammation and influential environmental factors Ghent University
The detrimental effects of poor ambient air quality, in particular fine dust (particulate matter), on human respiratory health are extensively studied and well known, in contrast to (farm) animals. Agricultural environments, in particular stables, are important sources of organic dust and emissions of other air pollutants like ammonia. In animals poor air quality induces airway inflammation and pneumonia, but the exact contributing factors ...
Clinical applications of computational cytometry Ghent University
Flow cytometry is an essential technique in the fields of immunology and oncology, allowing insights at the individual cell level at relatively low cost, complementary to genetics and other clinical parameters. Due to recent technological advancements, this field is moving towards more automated analysis approaches. In this research proposal, I will work on two methods to aid researchers using flow cytometry. First, I will develop an ...