Projects
Pulsed Laser Light and Nano-encapsulated Ocular Dyes for Advanced Therapies in the Eye Ghent University
Vision impairment is a major cause of disability. In Europe, an average of 1 in 30 people experience sight loss. Treatment of ocular diseases is a top priority today. However, the arsenal of medications remains rather restricted to traditional drugs despite improvements in pharmacological treatments. In this context, the EU-funded DYE-LIGHT project will explore new ways to deliver biotherapeutics and perform ocular surgery. Going beyond ...
Laser-induced nanobubbles for advanced therapies in the eye Ghent University
Ocular diseases affect the quality of life of millions of patients. Despite some improvements, the arsenal of medications to treat severe ocular diseases today remains rather restricted to traditional drugs. Use of modern biotherapeutics, like proteins and nucleic acids, could be a major step forward. However, current ways of administration, such as eye drops and intravitreal injections, are no longer sufficient to deliver these drugs to most ...
Laser-induced nanobubbles for advanced therapies in the eye. Ghent University
Ocular diseases affect the quality of life of millions of patients. Despite some improvements, the arsenal of medications to treat severe ocular diseases today remains rather restricted to traditional drugs. Use of modern biotherapeutics, like proteins and nucleic acids, could be a major step forward. However, current ways of administration, such as eye drops and intravitreal injections, are no longer sufficient to deliver these drugs to most ...
Opto-Biomechanical Eye Research Network (OBERON). University of Antwerp
Bio-impedance Sensor Technology for Robot-Assisted Vitreo-retinal Surgery KU Leuven
At present, vitreoretinal surgery is performed purely manually by highly specialized, welltrained surgeons. The surgeons need superior handeye coordination and precise positioning. When applying even small forces tangential to the surface of the eye, e.g. by means of the inserted instruments, the eye rotates and a different part of the eye becomes visible under the microscope. Microsurgeons are trained to pivot the instruments around the ...
The intra-ocular lens beyond cataract surgery KU Leuven
Cataract refers to any degree of opacification of the crystalline lens. It is the leading cause of preventable blindness in the world, whereas cataract extraction with intraocular lens (IOL) implantation is perhaps the most effective surgical procedure existing.
This project focuses on the optimization of various surgical techniques related to modern cataract surgery or phaco-emulsification (phaco).
Optimization of combined ...
ROCK inhibitors as novel antifibrotic strategy for glaucoma surgery. KU Leuven
Glaucoma is a chronic optic neuropathy which is characterized by the loss of retinal ganglion cells, resulting in irreversible visual field loss. It is the most important cause of irreversible blindness worldwide and with aging of the population the number of glaucoma patients is still expanding. Mostly the appearance of this disease is correlated with an increased intraocular pressure (IOP), due to an imbalance between aqueous humor ...
Modulation of wound healing after glaucoma surgery. KU Leuven
PASSAGE - Pioneering Autonomous Suturing for Single-port Access surGEry KU Leuven
Unlike conventional minimal invasive surgery (MIS), Single-port access surgery (SPA) utilizes only a single incision or a natural orifice to access the surgical space. While further reducing the risk for morbidity and shortening the recovery period, the single access approach magnifies the technical difficulties such as poor eye-hand coordination, limited vision and haptic feedback, notably in utero repair of open spina bifida. Recently a ...