Transient Receptor Potential Channels as Sensors of Extracellular Lipid Vesicles KU Leuven
Transient receptor potential (TRP) channels are ubiquitous molecular sensors of chemical, thermal and mechanical stimuli and are thereby involved in numerous physiological and pathophysiological processes and proposed as targets to treat multiple human diseases. TRP channels are activated by mechanical stimuli inducing shear stress and changes in membrane curvature and tension, and by the perturbations produced by insertion of chemicals in ...