Projects
Prevention of heart failure in type 2 diabetes by exercise intervention Ghent University
Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...
Prevention of heart failure in type 2 diabetes by exercise intervention KU Leuven
Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...
THORACIC SPINAL MOBILITY IN ADULTS: CLINICAL ASSESSMENTS AND EXERCISE INTERVENTION KU Leuven
The thoracic spine is one of the most under-researched regions of the spine. However, it is often treated by clinical therapists with manipulation or manual therapy techniques to reduce neck, shoulder, and lower back pain indirectly. High-quality, evidence-based research on the effects of exercise interventions as a treatment modality needs to be improved. It is believed that an increased curvature and lack of mobility of the thoracic spine ...
Prevention of heart failure in type 2 diabetes by exercise intervention Hasselt University
Prevention of heart failure in type 2 diabetes by exercise intervention KU Leuven
Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...
Prevention of heart failure in type 2 diabetes by exercise intervention KU Leuven
Heart failure is one of the most common complications in patients with type 2 diabetes. Exercise is suggested treatment strategy in type 2 diabetes. However, it is unkown which traing intensity and volume have the most protective influence on the cardiac structure and function. In this study we will recruit 182 pateints with type 2 diabetes in two Belgian regions (UHasselt - Jessa Ziekenhuis en KU Leuven - UZ Leuven, Belgian). Patient will ...
Dysfunctional atrial natriuretic peptide physiology in subcutaneous adipocytes of adults with obesity: etiology, relation with cardiometabolic risk, and impact of exercise intervention. Hasselt University
Unravelling the association between insulin sensitivity and brain metabolites in prediabetic individuals, and exploring the therapeutic impact of exercise as an early intervention Hasselt University
Towards a targeted therapy for diabetic neuropathy: a cross-sectional study and exercise training intervention to improve pathophysiological understanding. Ghent University
Approximately 50% of all patients with type 2 diabetes mellitus (T2DM) develop diabetic neuropathy (DNP), which leads to a decrease in muscle mass and strength. This sarcopenic effect can theoretically be attributed to a shift in muscle fiber type and a negative protein turnover, resulting from reduced mitochondrial function and inflammation. There are some studies that report a shift to a more anaerobic type IIx fibers in the case of T2DM, ...