Projects

Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...

Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...

Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...

The spine is divided into five regions namely the cervical (neck), thoracic (upper back), lumbar (lower back), sacral (pelvic area) and coccygeal (pelvic area). A lack of research investigating the upper back (thoracic spine) exists because most people experience lower back and neck pain. This leads to a gap in upper back research because many researchers investigate the spinal regions where most pain is localised. The lack of research on the ...

Heart failure is one of the most common complications in patients with type 2 diabetes. Exercise is suggested treatment strategy in type 2 diabetes. However, it is unkown which traing intensity and volume have the most protective influence on the cardiac structure and function. In this study we will recruit 182 pateints with type 2 diabetes in two Belgian regions (UHasselt - Jessa Ziekenhuis en KU Leuven - UZ Leuven, Belgian). Patient will ...

Insulin resistance (IR) has been linked to obesity, type 2 diabetes mellitus, and recently Alzheimer’s
disease. However, it is strikingly prevalent, even among young and lean individuals who are typically not considered at risk, making it a serious public health issue. Since the related pathologies are all linked to altered neurometabolism, early warning signs could already be observable in the prediabetic state. Because research on IR ...

Sarcopenia is the loss of muscle mass and function with ageing. It is a hot topic in geriatric medicine due to its increasing prevalence and far-reaching consequences such as immobility, falls, fractures and death. To treat sarcopenia, we developed the Exercise and Nutrition for Healthy AgeiNg (ENHANce) project, in which we examine the effect of proteins with or without omega-3 fatty-acid supplements on top of a physical exercise program. The ...