Publications
Programmatic management of rifampicin-resistant tuberculosis with standard regimen in Cameroon: a retrospective cohort study KU Leuven Institute of Tropical Medicine
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis. Institute of Tropical Medicine
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs University of Antwerp KU Leuven Institute of Tropical Medicine
Initial resistance to companion drugs should not be considered an exclusion criterion for the shorter multidrug-resistant tuberculosis treatment regimen University of Antwerp Institute of Tropical Medicine
Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis Institute of Tropical Medicine
We sought to compare the effectiveness of two World Health Organization (WHO)-recommended regimens for the treatment of rifampin- or multidrug-resistant (RR/MDR) tuberculosis (TB): a standardised regimen of 9-12 months (the "shorter regimen") and individualised regimens of >= 20 months ("longer regimens").
We collected individual patient data from observational studies identified through systematic reviews and a public call for ...
Treatment outcome with a short multidrug-resistant tuberculosis regimen in nine African countries Institute of Tropical Medicine
SETTING: Nine countries in West and Central Africa.
OBJECTIVE : To assess outcomes and adverse drug events of a standardised 9-month treatment regimen for multidrug-resistant tuberculosis (MDR-TB) among patients never previously treated with second-line drugs.
DESIGN: Prospective observational study of MDR-TB patients treated with a standardised 9-month regimen including moxifloxacin, clofazimine, ethambutol (EMB) and ...
Implications of failure to routinely diagnose resistance to second-line drugs in patients with rifampicin-resistant tuberculosis on Xpert MTB/RIF University of Antwerp
A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis Institute of Tropical Medicine
A clear understanding of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis is required to accelerate the development of rapid drug susceptibility testing methods based on genetic sequence.
Raw genotype-phenotype correlation data were extracted as part of a comprehensive systematic review to develop a standardised analytical approach for interpreting resistance associated mutations for rifampicin, isoniazid, ...