Projects
Exposure to airborne particles and ageing pathways in the ENVIRONAGE birth cohort: integrating inflamming pathways with telomeres Hasselt University
Transciptomics signatures of in utero exposure to polycyclic aromatic hydrocarbons in relation to the developmental origins of disease; the ENVIRONAGE birth cohort Hasselt University
The influence of early life environmental exposure on (epi)genetics: findings from the ENVIRONAGE birth cohort Hasselt University
Unravelling environmental exposures in the core axis of ageing Hasselt University
External and Internal Drivers of Unhealthy Ageing KU Leuven
Lead and cadmium are ubiquitous environmental toxicants, which at high exposure levels cause hypertension and renal failure. In the 1980s, Belgium was worldwide the second largest cadmium producer, using a pyrolytic refinement of zinc ore, whereby half of the production escaped into the environment. In the United States, lead-containing paint was only effectively banned in 1976 and leaded gasoline was completely phased out only in 1995. As ...
Advancing Pediatric Precision Healthcare: Integrating Rapid Metabotyping as a Fundamental Component for 4P Medicine through Source-Driven Metabolome Predictions Ghent University
The rising incidence of pediatric obesity and associated comorbidities has created an urgent need to identify effective therapeutic approaches. To address this problem, source-driven metabolite predictions (based on diet, microbiome, lifestyle and psychological parameters) are proposed, whereby links between metabolite sources and their biomarker signatures can be obtained as a basis towards individualization of treatments (4P principle). To ...