Publications
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Forever young: Endocrinology of paedomorphosis in the Mexican axolotl (Ambystoma mexicanum) KU Leuven
The Mexican axolotl (Ambystoma mexicanum) is a salamander species that does not undergo metamorphosis, resulting in the retention of juvenile characteristics in the mature breeding stage (paedomorphosis). Here we review the endocrinological studies investigating the proximate cause of axolotl paedomorphosis with a focus on the hypothalamo-pituitary-thyroid (HPT) axis. It is well established that axolotl paedomorphosis is a consequence of low ...
Endocrinology of prostate cancer KU Leuven
Vitamin D endocrinology on the cross-road between immunity and metabolism KU Leuven
The effects of vitamin D on the immune function have been recognized for more than a quarter of a century. However, our understanding of the multifactorial nature of the effects of vitamin D at the cellular, molecular and metabolic level in different immune cells of the innate and adaptive immune system has dramatically progressed during the last decades. In this review, we summarize the main metabolic pathways preferentially used in different ...
How functional genomics and genetics complements insect endocrinology KU Leuven
Insects are the most abundant animal group on Earth and have been the subject of genetic and physiological studies since the beginning of the 19th century. The public interest in understanding their biology increased as many insects have proven to exert a severe impact on human welfare and the environment. To trigger insect physiological and endocrinological research, the genome of several economical and ecological important insect species was ...
Endocrinology in the critically ill KU Leuven
Mechanisms in endocrinology University of Antwerp
Throughout life, bone is continuously remodelled to be able to fulfil its multiple functions. The importance of strictly regulating the bone remodelling process, which is defined by the sequential actions of osteoclasts and osteoblasts, is shown by a variety of disorders with abnormalities in bone mass and strength. The best known and most common example of such a disorder is osteoporosis, which is marked by a decreased bone mass and strength ...