Projects
The next generation of transmission electron microscopy: from biomedicine to nanomaterials. A state-of-the art electron microscopy system for cryo-EM and correlative light and electron microscopy. Hasselt University
3D super-resolution correlative light and electron microscopy on a dedicated CLEM microscope and development of an automated data acquisition KU Leuven
Fluorescence microscopy can provide information about location of specific protein molecules, by tagging them with fluorescent moieties, or by labeling them with fluorescent antibodies. However, this information is constraint by the limited resolution of the fluorescence microscope as well as by the absence of cellular context on the nano-scale. Therefore it is necessary to employ correlative light and electron microscopy (CLEM), which ...
Super-resolution optical microscopy and optical trapping of nanoparticles in the vacuum chamber of a scanning electron microscope KU Leuven
In 1986, Ashkin and coworkers proposed the use of tightly focused laser beams to manipulate individual micro-scale objects such as microparticles. Typically, micro- and nano-scale objects freely diffuse in the bulk solution. In the presence of an optical field, the particles can be trapped in the focal spot as a trapping potential is generated there. When several nanoparticles are trapped, they will generate an assembly inside the focus. ...
Innovative three-dimensional electron microscopy to boost the catalytic activity of core-shell nanostructures. University of Antwerp
Exploring adaptive optics in transmission electron microscopy. University of Antwerp
Development of new integrated FLUO/SEM microscopy modalities for electron diffraction and optical trapping KU Leuven
The study of the structure of nanocrystalline materials is often difficult as standard X-ray diffraction techniques break down for sub micrometer particles, especially when occurring in a mixture. This is resolved by trying to crystallize specific compounds in larger crystals, but this is often problematic and time consuming. State of the art single crystal X-ray diffraction moreover requires a trip to a synchrotron which creates unnecessary ...
Electron and X-ray microscopy Community for structural and chemical Imaging Techniques for Earth materials Ghent University
Understanding earth materials is critical to creating a sustainable, carbon-neutral society due to their involvement in many vital processes. Earth materials control the feasibility of subsurface energy storage, geothermal energy extraction, and are a source of critical elements for future-proof battery technologies. However, perturbations to geological systems can also result in hazards, such as human-induced earthquakes. If we want to ...