Projects
Put up a decision method for the vaccination policy in Flanders KU Leuven
In this research, the Flemish government calls for the development of a method that can help to make 'correct' decisions in the field of vaccination, not only based on purely scientific advice on 'the epidemiology of, each vaccineable infectious disease separately and therefore not in relation to vaccination options for other disorders ', but from a' broader scope a prioritization can be determined of the vaccinations that should be ...
HOSPITAL-BASED SURVEILLANCE OF ANTIMICROBIAL RESISTANCE IN GRAM-NEGATIVE BACTERIA IN PERU KU Leuven
The global emergence of antimicrobial resistance has been recognized as a major threat to human kind. Although antimicrobial resistance is a global problem, low and middle income countries, are disproportionally affected by this threat. Peru, a middle-income country, has one of the highest rates of resistance to third-generation cephalosporins among Gram-negative bacteria in Latin-American and worldwide. Importantly, these rates are ...
Impact of polyunsaturated fatty acids, lipid oxidation products, haem-Fe and nitrite salt in muscle foods on oxidative stress and the colon microbiome in rats. Ghent University
Red meat and fish are widely consumed, nutritious muscle-based foods with, however, opposing
epidemiologic associations with a range of chronic diseases. The underlying mechanisms are not
yet elucidated, but it is assumed that oxidative stress and alterations in the colon microbial
communities interfere. Previously, we showed through simulations of meat and fish
gastrointestinal digestion, that the fatty acid profile, ...
DiarY by Nurses' iMplemented in the Intensive Care unit. KU Leuven
Nursing is the largest healthcare discipline worldwide and nurses play vital roles in the healthcare system. Clinical guidelines and protocols are available to provide safe and effective nursing care, but implementing these in routine care is not easy. So far, nursing implementation science has provided little evidence to guide the development of implementation strategies for influencing nurses’ professional behaviors. The proposed research ...
Maternale obesitas en "fetal programming": de gevolgen voor de voortplantingsfysiologie van de nakomelingen. University of Antwerp
Identifying molecular mechanisms underlying the effects of ethanol on eukaryotic genome instability KU Leuven
Alcohol (ethanol) is toxic to all life forms and its consumption has been associated
with numerous diseases, including cancer. Epidemiological studies have identified
causal relationships between alcohol intake and the incidence of oral cavity, larynx,
pharynx, esophagus, liver, colorectum, and female breast cancer. Yet, the molecular
mechanisms underlying the carcinogenic effect of ethanol remain elusive. It is clear ...
Novel PET targets in stroke research KU Leuven
This thesis presents three novel PET targets in stroke research.
First we explore amyloid PET in the context of cerebral amyloid angiopathy. Cerebral amyloid angiopathy is a frequent cause of lobar intracerebral hemorrhage and is characterized by vascular amyloid β accumulation. Amyloid tracers, which were originally developed in the setting of Alzheimer disease, do not only bind to parenchymal amyloid plaques (as seen in Alzheimer ...