Development of photo-activatable protease inhibitors and activity-based probes and their application in the study of dynamic proteolytic processes KU Leuven
Proteases are involved in many highly regulated biological processes, such as apoptosis, cell-cell communication and blood coagulation. Inhibitors and activity-based probes (ABPs) have been successfully utilized as chemical tools to study these enzymes. However, when studying fast and dynamic processes, local and temporal acivation of these reagents is desirable. Such reagents can first of all be used for basic study of these processes, but ...
Total hip replacement (THR) is one of the most frequently performed orthopedic surgeries. Despite the fact that THR is a successful operation with relatively high survival rates, a large absolute number of revisions are needed. The main reason for revision is aseptic loosening, often caused by osteolysis, the process of bone resorption due to the excessive presence of particles, mostly PE particles originating from the implant. Attempts ...
Integrating molecular archeology and Bayesian phylodynamics to elucidate the hidden history of HIV-1. KU Leuven
Latin authority and constructional transparency at work: neologisms in the French medical vocabulary of the Middle Ages and their fate. KU Leuven
Zeolites are used industrially on a large scale in adsorption, ion exchange and catalysis, based on a plethora of advantageous physicochemical properties, which are combined with a relatively straightforward synthesis using mostly low-value commodity chemicals. In catalysis however, their activity is often hampered by the high amount of micropores present, causing mass diffusion limitations or even accessibility problems. In order to overcome ...
BREAZE - BREath analyser with ALD coated ZEolite Ghent University
Towards the development of ArcheoGML: a conceptual data model for a 4D archaeological GIS Ghent University
The proposed project consists of a first step towards a formal definition of a conceptual data model specifically designed for 4D archaeological data and analysis. The requirements of the archaeologists will take a central position in this development. The model will be gradually created using test cases on archaeological sites and continous feedback with the detected user requirements.