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Use of a live attenuated Salmonella enterica serovar Typhimurium vaccine on farrow-to-finish pig farms Ghent University
Fate of Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium in the manure-amended soil-plant ecosystem of Brassica oleracea under tropical field conditions in the Central Agro-Ecological Zone of Uganda KU Leuven
Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium are important enteric food-borne pathogens that are known to inhabit the gastrointestinal tract of ruminant animals. Decline in soil fertility and exorbitant costs of mineral fertilisers have stimulated the utilization of cattle manure as a fertiliser in fresh vegetable production by small-holder farmers in Sub-Saharan Africa. In most cases farmers apply the manure directly ...
Expression divergence between Escherichia coli and Salmonella enterica serovar Typhimurium reflects their lifestyles KU Leuven Ghent University University of Antwerp
Escherichia coli K12 is a commensal bacteria and one of the best-studied model organisms. Salmonella enterica serovar Typhimurium, on the other hand, is a facultative intracellular pathogen. These two prokaryotic species can be considered related phylogenetically and they share a large amount of their genetic material, which is commonly termed the 'core genome'. Despite their shared core genome, both species display very different life styles ...
Chemical synthesis of N-acyl homoserine lactone analogues and brominated furanones, and their biological activities with Salmonella enterica serovar Typhimurium and Vibrio spp. KU Leuven
Salmonella enterica is een Gram-negatieve ziekteverwekker en één van de voornaamste oorzaken van bacteriële voedselvergiftigingen. Gezien de sterke toename in het aantal Salmonella-stammen die resistent zijn tegen meerdere antibiotica en aangezien Salmonella biofilmen kan vormen op een brede waaier van vaste oppervlakken, waardoor de bacterie beter kan overleven buiten de gastheer, is het van groot belang om nieuwe therapeutica tegen deze ...
Porcine in vitro and in vivo models to assess the virulence of Salmonella enterica serovar Typhimurium for pigs Ghent University
Genetic and Structural Variation in the O-Antigen of Salmonella enterica Serovar Typhimurium Isolates Causing Bloodstream Infections in the Democratic Republic of the Congo KU Leuven Institute of Tropical Medicine University of Antwerp
Salmonella enterica serovar Typhimurium causes a devastating burden of invasive disease in sub-Saharan Africa with high levels of antimicrobial resistance. No licensed vaccine is available, but O-antigen-based candidates are in development, as the O-antigen moiety of lipopolysaccharides is the principal target of protective immunity. The vaccines under development are designed based on isolates with O-antigen O-acetylated at position C-2 of ...
Brominated furanones inhibit biofilm formation by Salmonella enterica serovar Typhimurium KU Leuven Ghent University
Salmonella enterica serovar Typhimurium is a main cause of bacterial food-borne diseases. As Salmonella can form biofilms in which it is better protected against antimicrobial agents on a wide diversity of surfaces, it is of interest to explore ways to inhibit biofilm formation. Brominated furanones, originally extracted from the marine alga Delisea pulchra, are known to interfere with biofilm formation in several pathogens. In this study, we ...
Genome-Scale Co-Expression Network Comparison across Escherichia coli and Salmonella enterica Serovar Typhimurium Reveals Significant Conservation at the Regulon Level of Local Regulators Despite Their Dissimilar Lifestyles KU Leuven Ghent University
Availability of genome-wide gene expression datasets provides the opportunity to study gene expression across different organisms under a plethora of experimental conditions. In our previous work, we developed an algorithm called COMODO (COnserved MODules across Organisms) that identifies conserved expression modules between two species. In the present study, we expanded COMODO to detect the co-expression conservation across three organisms by ...
Protective effects of milk fermented by Lactobacillus plantarum B7 from Brazilian artisanal cheese on a Salmonella enterica serovar Typhimurium infection in BALB/c mice KU Leuven University of Antwerp
© 2017 Milks fermented with Lactobacillus strains showing probiotic properties are an important tool to maintain gastrointestinal health. In this study, Lactobacillus plantarum (B7), from Brazilian artisanal cheese, was evaluated for its action against Salmonella enterica serov. Typhimurium, first by co-incubation and supernatant in vitro methods. In vivo, male BALBC/c mice received daily, for seven days, an oral dose of milk fermented by the B7 ...