Projects
Development of advanced osteoinductive stimuli-responsive core/shell nanocarriers for use in bone tissue regeneration. Hasselt University
Development of advanced osteoinductive stimuli-responsive core/shell nanocarriers for use in bone tissue regeneration. Hasselt University
Multivalent dual-responsive polymeric nanoparticles for targeted anti-cancer therapy Ghent University
In this project we aim to develop a formulation that selectively delivers anti-cancer drugs to cancer cells while minimizing unwanted toxicity to healthy tissue. For this purpose we will encapsulate hydrophobic anti-cancer agents in polymeric nanoparticles thate are engineered with (1) targeting ligands to selectively bind to cancer cells and (2) stimuli-responsive properties to release their drug payload only after cellular uptake.
Development of a microfluidic platform for self-governing selection of individual B-cells using bioresponsive hydrogels: a source of fully human therapeutic antibodies KU Leuven
Monoclonal antibodies (mAb) are the biggest class of biopharmaceuticals used against cancer, inflammatory and autoimmune diseases. As the ability of the human immune system to generate highly specific mAb is unmatched by any man-made approach, several technologies have been developed to generate fully human (FH)-mAb. Among those, single B-cell screening has emerged as a powerful technique. In this project, two KU Leuven groups will join their ...
Combining hybrid hydrogels with peptide conjugation for targeted cartilage tissue engineering Hasselt University
Combining hybrid hydrogels with peptide conjugation for targeted cartilage tissue engineering. Hasselt University
Utilizing interfacial impedance- and heat-transfer phenomena in advanced monitoring- and switching devices Hasselt University
Role of bioactive androgens in male osteoporosis. KU Leuven
Osteoporosis is a skeletal disease characterized by compromised bone strength predisposing to an increased risk of fractures. The lifetime risk of osteoporotic fractures is as high as 20-25% in Caucasian men, which accounts for about one-third of the societal and economic burden of the disease. Still, older men have about half the fracture risk of post-menopausal women, in part because men develop wider and stronger bones during puberty which ...
Oxytocin-based Pharmacotherapy for Autism Spectrum Disorder: Behavioral and Neural Effects of a Promising Intervention Approach KU Leuven
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by difficulties in social interaction and communication, and restricted interests and repetitive behaviors. Considering the increasing prevalence and high clinical, social and financial burden of ASD on society, there is a strong need for effective treatments. To date, therapeutic interventions mainly comprise behavioral social skills trainings, for which ...