Drug exposure through lactation: providing neonatal physiology to improve pharmacokinetic predictions KU Leuven
At present, there is little evidence-based advice on the intake of various drugs during pregnancy and lactation, with the result that a large percentage of medicines are not recommended during this period. Furthermore, there is a lack of scientific information on the effect of drugs in the neonate, more specifically on the pharmacokinetics of neonatal physiology. Because of the complex ethical dilemma, simulations are used to construct models ...