Publications
Chosen filters:
Chosen filters:
Drug interaction between propofol and remifentanil in individualised drug delivery systems Ghent University
Imaging of cells and nanoparticles: implications for drug delivery to the brain Ghent University
A major challenge in the development of central nervous system drugs is to obtain therapeutic effective drug concentrations inside the brain. Many potentially effective drugs have never reached clinical application because of poor brain penetration. Currently, devices are being developed that may improve drug delivery into the brain. One approach involves the encapsulation of drugs into nanocarriers that are targeted to the brain, where the drug ...
A simple non-invasive approach toward efficient transdermal drug delivery based on biodegradable particulate system Ghent University
Transdermal administration via skin appen- dages enables both localized and systemic drug delivery, as well as minimizes incidental toxicity. However, the design of an appropriate effective method for clinical use remains challenging. Here, we introduce calcium carbonate-based carriers for the transdermal transportation of bioactive substances. The proposed system presents easily manufactur- able biodegradable particles with a large surface area ...
Profluorescent PPV-based Micellar System as a Versatile Probe for Bioimaging and Drug Delivery Hasselt University
Although micelles are commonly used for drug delivery purposes, their long-term fate is often unknown due to photobleaching of the fluorescent labels or the use of toxic materials. Here, we present a metal-free, nontoxic, nonbleaching, fluorescent micelle that can address these shortcomings. A simple, yet versatile, profluorescent micellar system, built from amphiphilic poly(p-phenylenevinylene) (PPV) block copolymers, for use in drug delivery ...