Projects
IOF GEAR: µFlow cel Vrije Universiteit Brussel
Design and develop innovative microfluidic solutions within the core research lines of the consortium.
Fabricate and ...
PeRsOnalized nutriTion for hEalthy livINg. KU Leuven
Proper nutrition is essential for good health, well-being and the prevention, mitigation or treatment of a number of non-communicable diseases (NCDs). Food is not only a source of calories, but also a complex mixture of dietary chemicals, some of which are directly related to cardiovascular diseases, diabetes, allergies and some types of cancer. Foods, diet and nutritional status, including overweight and obesity, are also associated with ...
PROTEIN: PeRsOnalized nutriTion for hEalthy livINg Vrije Universiteit Brussel
ASSESSMENT AND IMPROVEMENT OF DIETARY INTAKE OF MICRONUTRIENTS (ZINC, IRON AND COPPER): A TRIAL OF COMMON BEANS (Phaseolus vulgaris L.) IN MAKUENI, KENYA. KU Leuven
Background: Under nutrition continues to be a challenge in Kenya with micronutrient deficiencies being prevalent. Legumes are affordable and very good sources of proteins, vitamins and minerals. Their consumption remains low, possibly due to concerns about flatulence, long cooking times and attitudes that view them as inferior foods. They are widely available in Kenya therefore promoting consumption of their improved products would have high ...
Determinants and effects of mergers and acquisitions on innovation: Evidence from drug projects in the pharmaceutical industry KU Leuven
Innovation is essential for progress, long-term growth, and consumer welfare. As such, there is almost a universal consensus among economists that innovation must be not only protected but promoted. However, research remains unclear as regards the role competition plays in pursuing this goal. The relationship between competition and innovation is complex and ambiguous (Aghion et al., 2005; Shapiro, 2011). Discussions are thus still ongoing ...
Multispectral Speckle Plethysmography investigating its Origin in Tissue by comparing Temporal and Morphological Features with Clinical References KU Leuven
Background
Monitoring of hemodynamic variables is a cornerstone of modern medicine which has facilitated the diagnosis and analysis of many diseases. The main methods for different types of hemodynamic monitoring used in medical settings include electrocardiogram (ECG), continuous finger arterial pressure monitors (fiAP), photoplethysmography (PPG), and continuous wave doppler flowmetry. However, lack of continuity and specificity of ...
Unraveling the contribution of oligodendrocytes to neurodegeneration: a new look at Wolfram's disease. KU Leuven
Wolfram syndrome is a rare hereditary disease, causing diabetes, blindness, deafness and other neurological problems in infants and young adults, and results in death around the age of 30 years. Wolfram patients carry recessive mutations in the WFS1 gene, resulting in loss of function of the WFS1 protein. Loss of WFS1 has been shown to result in ER stress, dysregulated Ca2+ homeostasis and mitochondrial dysfunction. Remarkably, in the brains ...
Decipher the function of TRPV2 in trophoblast giant cells. KU Leuven
Intrauterine growth restriction (IUGR) refers to the failure of the fetus to achieve its genetically determined growth potential and affects up to 5-10% of pregnancies. Growth restricted neonates have increased perinatal mortality rates and are more susceptible to develop adult metabolic diseases. Our unpublished results showed that mice lacking TRPV2 display late-onset IUGR caused by placental weight deceleration at E15.5, followed by fetal ...
Combining lower doses of glucocorticoids with mineralocorticoid receptor antagonists as a novel drug repurposing strategy in multiple myeloma Ghent University
Multiple myeloma (MM) is an incurable lymphoid malignancy characterized by an uncontrolled accumulation of plasma cells in the bone marrow and represents 10% of all hematological cancers. Approximately 800 patients are diagnosed annually with MM in Belgium. Today, newly diagnosed patients are usually treated with combinations consisting of proteasome inhibitors (e.g. bortezomib), immunomodulatory drugs (e.g. thalidomide, lenalidomide) and ...