Stem Cell and Developmental Biology KU Leuven
research
1. Pluripotent Stem Cells and Reprogramming
2. Pluripotent Stem Cell Differentiation
3. Adult Stem Cells
4. Disease Modelling and Regenerative Therapies
research
1. Pluripotent Stem Cells and Reprogramming
2. Pluripotent Stem Cell Differentiation
3. Adult Stem Cells
4. Disease Modelling and Regenerative Therapies
Correlations between echocardiographic, angiocardiographic and anatomical data in children with congenital heart malformations. Exercice tolerance studies in children before and after surgery for congenital heart malformations (gas exchange, determination of the ventilatory anaerobic threshold). (in collaboration with Dr. T. Reybrouck).
Basic aims of the Follicle Biology Laboratory, led by Prof. Ellen Anckaert are the design and validation of new culture systems for ovarian follicles and unripe egg cells to establish practical, applicable strategies for fertility clinics.
Fundamental and pre-clinical research:
1) optimization of multistep systems for in vitro follicle activation, growth and maturation: mouse in vitro models for culturing ovarian follicles ...
The Skeletal Biology and Engineering Research Center focuses its research on the understanding of the cellular and molecular basis of skeletal tissue formation, remodeling and repair.
The Center thereby aims to develop treatments for skeletal disorders, in particular regenerative strategies for cartilage, bone and joint repair. These approaches include the manufacturing of novel class Advanced Therapeutic Medicinal Products, towards we ...
The Laboratory of Synapse Biology aims to unravel the molecular mechanisms that control neuronal connectivity in developing circuits, and determine how perturbations in this process affect cognitive function.
The Laboratory of Behavioral and Developmental Genetics researches Gene circuits in Drosophila brain development as models for human neurodevelopmental disorders from transcription factors to effector genes and signaling pathways.
The long-term objectives of their research comprise:
We want to force a breakthrough in the cure of neuronal and neurodegenerative disorders. This requires a deep understanding of normal brain function and translation of this knowledge into a solid mechanistic understanding of disease mechanisms.
The research of the Laboratory of Developmental Signaling consists of topics from three research lines:
Information processing in the brain depends on specialized circuits that are formed by distinct types of neurons. How these different nerve cells emerge and mature during development remains a fundamental question in neurobiology. We are interested to define at single-cell resolution the metabolic and transcriptomic programmes that shape neuronal diversity and circuit assembly in the developing mammalian cortex. Our research focuses primarily ...