To co-opt or destroy: Understanding the mechanisms driving replacement or destructive histological growth patterns in liver metastasis. KU Leuven
Blending in with your surroundings is a tactic that many organisms use to disguise their appearance. Strikingly, also metastatic tumors are very efficient at hiding within the existing tissue structures. One particular way is to adapt to the existing tissue structure by replacing the surrounding healthy epithelial cells and subsequently making use of the healthy tissue infrastructure, such as supply of nutrients by blood vessels, to drive ...