Projects
OrBITS Platform: A Cloud-Based Image Analysis and Drug Screening Service. University of Antwerp
A combination of Multi-Electrode Array (MEA) and Live Mouse Tracker (LMT) as a versatile drug screening platform for Fragile X syndrome. University of Antwerp
A combination of Live Mouse Tracker (LMT) and Multi-Electrode Array (MEA) as a versatile drug screening platform for fragile X syndrome. University of Antwerp
Beyond transplantation: Combining high throughput and virtual drug screening to develop an innovative eye drop for corneal endothelial regeneration. University of Antwerp
New machine-vision and automation methods for high throughput combinatorial drug screening KU Leuven
Next Generation Screening in Quantitative Biology & Drug Discovery KU Leuven
In this proposal we outline a state-of-the-art platform that would be among the first in Europe to combine the best in automated microscopy with advanced cell culture robotics capable of automated isolation, expansion and differentiation of mammalian and human cells, including iPSC. The platform will be unique in Flanders and will allow running quantitative image-based screens as well as screens for disease phenotypes using conventional cell ...
Empowering precision medicine in melanoma: Exploring the potential of an implantable microdevice for large-scale drug screening in vivo KU Leuven
Cutaneous melanoma is the deadliest form of skin cancer and one of the most rapidly increasing malignancies in Caucasian populations worldwide. While advanced therapeutic options, such as targeted therapies and immunotherapy, have transformed melanoma treatment and improved overall survival, a substantial portion of the patients will face resistance and progressive disease. A widespread strategy to overcome these limitations is to combine ...
Artificial Lithographic MODel for COrNeal drug Screening Ghent University
The cornea is the transparent window to the eye and as such, eye drops are an interesting route of drug administration. In this project, we propose the development of a 3D corneal cell model that can be used to investigate corneal drug interaction. Studies that aim to simulate the pharmacokinetics and toxicological properties of drugs are mainly based on oversimplified 2D monocultures or animal studies that suffer from interspecies ...