Projects
Sequencing DNA of museum specimens to uncover the genetic basis of rapid adaptation to heavy fishing. University of Antwerp
PromethION: nanopore sequencer for high-throughput and long read high-fidelity DNA and RNA sequencing allowing fast decoding of (epi)genomes and (epi)transcriptomes Ghent University
The PromethION (Oxford Nanopore) is a standalone benchtop instrument designed for highthroughput, high-sample number nanopore sequencing. This third generation sequencing technology allows unprecedented opportunities such as direct epitranscriptome analysis, sequencing of extremely long reads and real-time data analysis. This groundbreaking technology differs from the
mostly used second generation short-read sequencing and allows ...
Next generation DNA sequencing. Socio-ethical analysis of standardization in decision and communication patterns of test results KU Leuven
Research on Rapid Metagenomic Analysis through Nanopore Sequencing HOWEST
Integrating long-read metagenomics sequencing in precision medicine and antibiotic stewardship for acute respiratory tract infections. University of Antwerp
LeapSEQ: Lean data processing solutions for adaptive and portable genome sequencing, applied to infectious disease monitoring. University of Antwerp
Nanopore sequencing of complete pharmacogenes after CRISPR/Cas9 enrichment in tamoxifen and clopidogrel patients allowing enhanced haplotyping and continuous scale machine learning efficacy prediction. Ghent University
Pharmacogenetics (PGx) studies how genes influence individual response to drug therapies. Current massively parallel short-read DNA sequencing (SR-MPS) technologies provide limited haplotype information. We want to alleviate this by developing full-gene long-read MPS on PGx genes using an amplification-free CRISPR/Cas9 target enrichment method. Completely-phased genotype data and metadata from 2 cohorts will be used to train a machine ...