Publications
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Inequalities in the burden of non-communicable diseases across European countries : a systematic analysis of the Global Burden of Disease 2019 study Ghent University
Pulmonary vascular disease in pulmonary hypertension due to left heart disease: pathophysiologic implications Hasselt University Vrije Universiteit Brussel
Aims Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in left heart disease (LHD). This study sought to characterize the pathophysiology of PVD across the spectrum of PH in LHD. Methods and results Patients with PH-LHD [mean pulmonary artery (PA) pressure >20 mmHg and PA wedge pressure (PAWP) >= 15 mmHg] and controls free of PH or LHD underwent invasive haemodynamic exercise ...
Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity KU Leuven Ghent University
ABSTRACT: INTRODUCTION: This study is based on the results from a Belgian expanded access program in which patients with active refractory and erosive rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab in combination with methotrexate. The objectives of this study were to evaluate the continuation rate of infliximab and its clinical effect over a 7-year period and to document the reasons for discontinuation. METHODS: ...
Predicting outcomes to optimize disease management in inflammatory bowel diseases Ghent University KU Leuven
Cardiovascular diseases : heart failure, coronary artery disease, arrhythmias, and hypertension Ghent University
Global Burden of Animal Diseases : a novel approach to understanding and managing disease in livestock and aquaculture Ghent University
Investments in animal health and Veterinary Services can have a measurable impact on the health of people and the environment. These investments require a baseline metric that describes the burden of animal health and welfare in order to justify and prioritise resource allocation and from which to measure the impact of interventions. This paper is part of a process of scientific enquiry in which problems are identified and solutions sought in an ...
Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries KU Leuven University of Antwerp Hasselt University
AIMS: Patients with cardiac disease are considered high risk for poor outcomes following hospitalization with COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart disease subtypes and in-hospital mortality. METHODS AND RESULTS: We used data from the CAPACITY-COVID registry and LEOSS study. Multivariable Poisson regression models were fitted to assess the association between different types ...