Projects
Infection mechanism of Diplodia corticola Ghent University
A progressive decline of oak tress in the Iberian Penisula has been increasingly recognised over the last two decades. An important cause of this decline is the fungus Diplodia corticola. We will use a proteomic approach to unravel the mode of action of this plant pathogen.
Shaping cortical interneuron identity by excitatory neurons. KU Leuven
Understanding the effect of cortical lateralization on selective motor control of the arm swing during independent walking after stroke. Ghent University
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke. Nevertheless, in current post-stroke gait rehabilitation (research) the upper limbs are barely targeted. To address this gap, my project aims to investigate the selective motor control of the upper limbs during walking and the contribution of the cortical activity to the arm swing in independent walkers after stroke. To gain ...
Deciphering the role of TMEM106B in neurodegeneration using a humanized cortical neuronal xenotransplantation model. University of Antwerp
The impact of the hominid-specific receptor LRRC37B on cortical circuit function, plasticity and diseases. KU Leuven
The impact of the hominid-specific receptor LRRC37B on cortical circuit function, plasticity and diseases.The cerebral cortex has undergone remarkable evolution in the Homo lineage, resulting in enhanced cognitive abilities. Recent work has revealed that human cortical neurons display species-specific functional features, such as enhanced electrical compartmentalization and decreased excitability, but the underlying molecular mechanisms, and ...
Shining light on higher-order thalamic and cortical networks of flexible visual behavior (VI-FLEX) KU Leuven
Vision is a vital sense and an essential source of sensory information for understanding and interacting with the world. The visual system, a dense network of cortical and sub-cortical areas, plays a critical role in transforming visual information into behaviors. However, little is known about how this entire network selects or prioritizes behaviorally-relevant sensory signals.
I postulate that higher-order thalamic nuclei (LP, ...
The role of astrocytes in cortical plasticity KU Leuven
A project summary with crafted with the advisor prior to project start.
Defining the STAT3-VEGF pathway to connect marrow and cortical bone vasculature KU Leuven
The skeletal system fulfils three major functions – structural, metabolic, and hematopoietic, linked via cellular interactions. These interactions occur between stromal cells, that differentiate into osteoblasts and the osteocyte network, and the vasculature. I hypothesise that these two cell types facilitate the closure of cortical vascular channels during cortical bone formation, and the expansion of these channels during ageing. High ...
Localizing Cortical Reward Prediction Error Signals Using Combined EEG and fMRI Ghent University
ACC may be involved in reward processing, which is reflected in EEG as 'reward positivity' . We aim to eatablish which part of the brain is producing the reward positivity. A novel design--a combined fMRI/EEG study with a modified time-estimation task will be conducted to explore this question, which will also help clear the role of ACC in reinforcement learning.