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Anthericaceae, Burmanniaceae, Colchicaceae, Crassulaceae, Dipterocarpaceae, Lemnaceae, Pittosporaceae, Rosaceae, Ternstroemiaceae, Thismiaceae, Triuridaceae Meise Botanic Garden
An HPLC method for the quantification of colchicine and colchicine derivatives in gloriosa superba seeds University of Antwerp
An 80% ethanolic extract of Gloriosa superba L. seeds (glory lily, Colchicaceae), as well as a colchicine-poor/colchicoside-rich extract, were shown to exhibit antitumor activity in a murine model for pancreatic cancer. Phytochemical investigations of the 80% ethanolic extract led to the identification of colchicine, 3-O-demethylcolchicine, and colchicoside. The objective of this work was to develop and validate a high performance liquid ...
Coadministration of a Gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour model University of Antwerp
Background Gloriosa superba L. (glory lily, Colchicaceae) contains colchicine, and related alkaloids such as 3-O-demethylcolchicine and its glycoside colchicoside. Previously the in vivo efficacy of a crude extract and a colchicine-poor / colchicoside-rich extract of G. superba seeds was shown in a murine model of pancreatic adenocarcinoma. Hypothesis/Purpose The efficacy can be improved without obvious signs of toxicity by increasing the ...
Chorological and taxonomic notes on African plants Meise Botanic Garden
This paper presents notes on new records and the taxonomy of 12 vascular plant species from several continental African countries and Madagascar. Datura wrightii (Solanaceae) is a new species for Africa reported from Morocco. Amaranthus muricatus (Amaranthaceae) is reported for the first time in Tunisia, Barleria oenotheroides (Acanthaceae) – from Central African Republic and Senegal, Burkea africana (Fabaceae) – from Guinea-Bissau, Caylusea ...
Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using 18F-FDG PET/CT for Monitoring Treatment Response KU Leuven University of Antwerp
PURPOSE: In vivo efficacy of two herbal extracts of Gloriosa superba L. (Colchicaceae) was investigated in a murine pancreatic tumor model by tumor volume measurements and Positron Emission Tomography (PET) imaging using 2-deoxy-2-[(18)F]fluoro-d-glucose ((18)F-FDG). MATERIALS AND METHODS: A crude extract of G. superba (GS) seeds rich in colchicine and a colchicine-poor extract (GS2B) containing mostly colchicoside as a putative prodrug were ...