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Design approaches for executable clinical pathways at the point of care in limited resource settings to support the clinical decision process: review of the state of the art Vrije Universiteit Brussel
Decision support clinical pathways are used to improve the performance of the health-care management system. An effective clinical pathway(CP) helps to know the optimal treatment route that patients will follow. The extent of the CP goes from the first contact in the health-center(or hospital) to the completion of the treatment until the patient is dismissed. Up to now, far too little attention has been paid to a systematic review, the research ...
Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria University of Antwerp
Background Routine viral load monitoring of patients on antiretroviral therapy (ART) is not affordable in most resource-limited settings. Methods A cross-sectional study of 496 Ugandans established on ART was performed at the Infectious Diseases Institute, Kampala, Uganda. Adherence, clinical and laboratory parameters were assessed for their relationship with viral failure by multivariate logistic regression. A clinical algorithm using targeted ...
Can Virtual Reality Ever Be Implemented in Routine Clinical Settings? A Systematic Narrative Review of Clinical Procedures Contained Within Case Reports for the Treatment of PTSD KU Leuven
The evidence base for the use of immersive technologies, such as Virtual Reality (VR), for the treatment of Post-Traumatic Stress Disorder (PTSD) is compelling. Despite promising results wide spread use and adoption of this technology within routine clinical practice remains limited. A lack of detailed technical guidelines might be one of the reasons that hamper such uptake. To address this gap, the current review focuses on earlier design ...
Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria Institute of Tropical Medicine
A hybrid approach for designing dynamic and data-driven clinical pathways point of care instruments in low resource settings Vrije Universiteit Brussel
Though a clinical pathway is one of the tools used to guide evidence-based healthcare, promoting the practice of evi- dence-based decisions on healthcare services is incredibly challenging in low resource settings (LRS). This paper pro- posed a novel approach for designing an automated and dy- namic generation of clinical pathways (CPs) in LRS through a hybrid (knowledge-based and data-driven based) algorithm that works with limited clinical ...
Implementation of quality management for clinical bacteriology in low-resource settings Institute of Tropical Medicine KU Leuven
BACKGROUND: The declining trend of malaria and the recent prioritization of containment of antimicrobial resistance have created a momentum to implement clinical bacteriology in low-resource settings (LRS). Successful implementation relies on guidance by a quality management system (QMS). Over the past decade, international initiatives were launched towards implementation of QMS in HIV/AIDS, tuberculosis and malaria.
AIMS: To describe ...
Best Practices for Long-Term Monitoring and Follow-Up of Alemtuzumab-Treated MS Patients in Real-World Clinical Settings Hasselt University
Multiple sclerosis (MS) is a chronic autoimmune neurological disease that typically affects young adults, causing irreversible physical disability and cognitive impairment. Alemtuzumab, administered intravenously as 2 initial courses of 12 mg/day (5 consecutive days at baseline, and 3 consecutive days 12 months later), resulted in significantly greater improvements in clinical and MRI outcomes vs. subcutaneous interferon beta-1a over 2 years in ...
Clinical HIV/AIDS care guidelines for resource-poor settings; 2nd ed Institute of Tropical Medicine
Validation of a clinical prediction score to target viral load testing in adults with suspected first line treatment failure in resource-constrained settings Institute of Tropical Medicine
BACKGROUND:: Whereas routine viral load (VL) monitoring currently is too costly for poor countries, clinical failure criteria perform poorly. We previously developed an algorithm combining a clinical predictor score (CPS) with targeted VL testing in a Cambodian patient population (derivation population). We now prospectively validate the algorithm in the same clinical setting (validation population), assess its operational performance and ...