Projects
Tackling FRAILTY: ACTIVE-AGE@home: a home-based functional exercise program for community dwelling frail older adults. University of Antwerp
Understanding mitochondrial function and the role of exogenous ketone supplementation in combating exercise intolerance and chronic fatigue in long COVID. Vrije Universiteit Brussel
term effects (long COVID). The symptoms (mostly fatigue and postexertional symptom exacerbation (PESE)) influence the life of these
patients. The current guidelines for rehabilitation are insufficient and
the pathogenesis is not fully understood. The first aim is to
understand the role of mitochondrial function (MF) in long COVID,
using a ...
How to improve muscle power at old age? Stair climbing as key exercise to detect and prevent functional disability KU Leuven
The ability of the muscles to generate force quickly, also referred to as power, is crucial in daily activities. Consequently, reduced muscle power has been proposed as an important predictor of age-related decline in functional performance. Optimally, functional assessments should both be applicable in clinical settings and sensitive to changes. This would enable frequent assessments and thus to initiate preventive programs in time. Stair ...
Start-to-Sport – Feasibility and efficacy of individualized, telemonitored, home-based exercise for adolescents and adults with congenital heart disease KU Leuven
Almost 1% of all baby’s is born with a heart defect (CHD) and most of them survive. Even though outcomes are good, they need lifelong follow-up because of a higher risk for cardiovascular diseases. Studies have shown that patients with CHD are not active enough and that a substantial amount of patients is overweight. Hence preventive strategies and education should not only focus on the heart problem, but also on a healthy lifestyle including ...
TBM (Applied Biomedical Research with a Primary Societal finality) project : Tackling FRAILTY: ACTIVE-AGE@home: a home-based functional exercise program for community dwelling frail older adults Vrije Universiteit Brussel
Flanders, emphasising vulnerable people in the community, involving
family and volunteers while focussing on health promotion to counter
sedentary lifestyle.Despite the high level of evidence for physical activity
(PA) as a countermeasure for frailty, the current Flemish standard of care
does not include structural PA interventions for ...
Pressure and volume registration of the right ventricle, during exercise, in patients with pulmonary hypertension. KU Leuven
The degree of RV dysfunction is an important determinant of mortality and exercise capacity in cardiopulmonary disease. Unfortunately, detection of RV dysfunction is most often delayed, when impairment is severe. Early detection could have important clinical implications for the management of these patients. Furthermore, demonstration of RV dysfunction during exercise might help explain symptoms such as exertional dyspnea or exercise ...
The association between new parameters of glycaemic control and arterial stiffness in type 1 diabetes, and its modulation by high-intensity interval exercise. Ghent University
BACKGROUND 1. New parameters of glycaemic control by use of continuous glucose monitoring (CGM; such as time in range, glycaemic variability) are of increasing interest in type 1 diabetes (T1DM) clinical practice. Poor glycaemic control negatively affects arterial stiffness, a valuable predictor for cardiovascular disease. However, reliable data using the state-of-the-art methodology (i.e. CGM) are missing. 2. Easy implementable strategies to ...
Unravelling the role of epigenetic modifications in response to exercise in patients with chronic widespread pain: an experimental study Vrije Universiteit Brussel
exercise can actually worsen symptoms in patients with chronic
widespread pain (CWP), thus preventing them from engaging in
regular physical activity. Unravelling the link between exercise
intolerance and pain is thus crucial to understand CWP
pathophysiology and develop truly effective treatments. Epigenetic
mechanisms provide core ...
Metabolic syndrome in bipolar disorder: relationships with physical activity, physical fitness and functional exercise capacity. KU Leuven
Individuals with mood disorders have a high risk for cardiovascular diseases. The lack of physical activity and a limited physical fitness are known to be important risk factors for cardiovascular diseases. Individuals with mood disorders should therefore especially be motivated to adopt an active lifestyle. In order to offer clear guidelines, there is first need for reliable assessment. In this research project we want to evaluate the ...